Upstream Processing Unit / Cell Culture (USP)
- Upstream cell culture and fermentation process development using QbD principles. Process characterization and optimization enabled by spent media and metabolite flux analysis. Process Scale up from shake flask to commercial scale bioreactor.
- Supported by infrastructure, such as, Glass and SS Bioreactors, Segregated Areas for Specific Functioning, e.g. Media Preparation, Microbiology, Fermentation, Sterilization etc. Fermenters with full online process control (MFCS), Cell Disruptors (Constant Systems) and Homogenizers, Biosafety cabinets, Incubator Shakers, High speed centrifuges, Phase contrast Microscope, Biochemical Analyzer, Autoclaves, etc.